Research Reference
MOTS-C — Reconstitution & Research Guide
MOTS-C acts on mitochondrial-derived peptide and is studied for metabolism & insulin-sensitivity research (preclinical / early research). Below: what the research covers, how to reconstitute and verify a vial, and reference values from the literature — framed strictly for laboratory research.
Research use only. This page is a research and laboratory-reference resource — mechanism, reconstitution math, and reference values from published research. It provides no human, veterinary, therapeutic, diagnostic, or administration guidance. Compounds sold by Renova Wellness™ are not approved for human or animal consumption.
Quickstart
Category
metabolic
Vial sizes
10 mg
Reconstitution
10 mg in 2 mL → 5 mg/mL
Reference amount
5–10 mg (research literature) · ~100 units/draw
Per-batch COA
HPLC purity + mass-spec identity
Storage
Frozen (lyophilized) · 2–8°C reconstituted
What the research covers
MOTS-C acts on Mitochondrial-derived peptide and is studied for metabolism & insulin-sensitivity research. Research status: preclinical / early research. The evidence base is largely preclinical and mechanistic; this section summarizes what published work has examined, not outcomes for any product. See the full cited overview in the MOTS-C research guide.
Reconstitution & calculator
Reconstitution is arithmetic: concentration = mg ÷ mL. A tidy option is 1 mL for a round 10 mg/mL (1 mg = 10 units). The tool below is pre-loaded for MOTS-C; type a vial and reference amount and it returns the clean-tick water options, U-100 units, and draws per vial.
Nova — Renova’s research assistant
Guided reconstitution · ⚡ Powered by Claude
- 1Draw 2 mL of bacteriostatic water (the volume set in the calculator above) and add it slowly down the inside wall of the vial.
- 2Swirl gently until fully dissolved — do not shake. The reconstituted solution should be clear.
- 3Label the vial with the date.
- 4Refrigerate at 2–8°C, protected from light, and use within the handling window below.
Supply reference
At a 5 mg reference amount, a 10 mg vial yields about 2 draws — roughly 0.7 weeks at 3 draws/week. Adjust the amount and cadence in the calculator to plan your own research schedule.
Shop MOTS-C →Storage & handling
- • Lyophilized: keep frozen, protected from light and moisture.
- • Reconstituted: refrigerate at 2–8°C, protected from light.
- • Avoid freeze–thaw of the reconstituted solution.
- • Allow a frozen vial to reach room temperature before opening. Read the storage guide.
Verify before you trust it
Every MOTS-C lot is third-party tested and ships with its own per-batch Certificate of Analysis — HPLC purity and mass-spectrometry identity, tied to the lot number on your vial. Don’t take our word for it: confirm the exact lot yourself.
MOTS-C FAQ
How do I reconstitute MOTS-C?+
MOTS-C ships lyophilized and is reconstituted with bacteriostatic water. Divide the mg in the vial by the mL of water for the concentration: a 10 mg vial in 2 mL is 5 mg/mL. Use the calculator on this page for other volumes. This is laboratory math, not a protocol.
What are the reference amounts for MOTS-C?+
In the research literature MOTS-C is commonly referenced around 5–10 mg (research literature). At a 10 mg vial in 2 mL that's about 100 units on a U-100 syringe for a 5 mg draw. These are reference values from published research — not a dose, recommendation, or instruction.
How is MOTS-C verified for purity?+
Every Renova Wellness lot ships with its own per-batch Certificate of Analysis — identity by mass spectrometry and purity by HPLC, tied to the lot number on the vial. You can confirm any lot yourself on the verification page before it leaves the bench.
How should MOTS-C be stored?+
Lyophilized vials are kept frozen, protected from light and moisture. Once reconstituted with bacteriostatic water, the solution is refrigerated at 2–8°C, protected from light, and avoided from freeze–thaw cycles. General laboratory-handling reference only.
Research references
Primary literature for MOTS-C. Provided for scientific context only — not medical or dosing guidance.
- Lee C, et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab. 2015. PMID 25738459 →
- Reynolds JC, et al. MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Nat Commun. 2021. PMID 33473109 →
Research Use Only
Sold strictly for in-vitro laboratory and scientific research. Not for human or animal consumption. Not a drug, supplement, or medical device. These statements have not been evaluated by the FDA.