GnRH

Gonadotropin-releasing hormone (GnRH) is produced by hypothalamic neurons and prompts the pituitary to secrete the gonadotropins that regulate the reproductive axis. Its pulsatile release is a core variable in neuroendocrine research.

Kisspeptin research is centered on GnRH neurons: kisspeptin acting at KISS1R is studied as a direct stimulus of GnRH release. This describes signaling pathways for laboratory reference only.