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Research Reference

GHK-Cu — Reconstitution & Research Guide

GHK-Cu acts on copper-binding tripeptide and is studied for collagen & senescence research (preclinical / cell models). Below: what the research covers, how to reconstitute and verify a vial, and reference values from the literature — framed strictly for laboratory research.

Research use only. This page is a research and laboratory-reference resource — mechanism, reconstitution math, and reference values from published research. It provides no human, veterinary, therapeutic, diagnostic, or administration guidance. Compounds sold by Renova Wellness™ are not approved for human or animal consumption.

Quickstart

Category

dermal

Vial sizes

50 / 100 mg

Reconstitution

50 mg in 3 mL → 16.67 mg/mL

Reference amount

1–2 mg (research literature) · ~6 units/draw

Per-batch COA

HPLC purity + mass-spec identity

Storage

Frozen (lyophilized) · 2–8°C reconstituted

What the research covers

GHK-Cu acts on Copper-binding tripeptide and is studied for collagen & senescence research. Research status: preclinical / cell models. The evidence base is largely preclinical and mechanistic; this section summarizes what published work has examined, not outcomes for any product. See the full cited overview in the GHK-Cu research guide.

Reconstitution & calculator

Reconstitution is arithmetic: concentration = mg ÷ mL. A tidy option is 5 mL for a round 10 mg/mL (1 mg = 10 units). The tool below is pre-loaded for GHK-Cu; type a vial and reference amount and it returns the clean-tick water options, U-100 units, and draws per vial.

Nova — Renova’s research assistant

Guided reconstitution · Powered by Claude

Research use only · not medical advice

  1. 1Draw 3 mL of bacteriostatic water (the volume set in the calculator above) and add it slowly down the inside wall of the vial.
  2. 2Swirl gently until fully dissolved — do not shake. The reconstituted solution should be clear.
  3. 3Label the vial with the date.
  4. 4Refrigerate at 2–8°C, protected from light, and use within the handling window below.

Supply reference

At a 1 mg reference amount, a 50 mg vial yields about 50 draws — roughly 16.7 weeks at 3 draws/week. Adjust the amount and cadence in the calculator to plan your own research schedule.

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Storage & handling

  • Lyophilized: keep frozen, protected from light and moisture.
  • Reconstituted: refrigerate at 2–8°C, protected from light.
  • Avoid freeze–thaw of the reconstituted solution.
  • • Allow a frozen vial to reach room temperature before opening. Read the storage guide.

Verify before you trust it

Every GHK-Cu lot is third-party tested and ships with its own per-batch Certificate of Analysis — HPLC purity and mass-spectrometry identity, tied to the lot number on your vial. Don’t take our word for it: confirm the exact lot yourself.

GHK-Cu FAQ

How do I reconstitute GHK-Cu?+

GHK-Cu ships lyophilized and is reconstituted with bacteriostatic water. Divide the mg in the vial by the mL of water for the concentration: a 50 mg vial in 3 mL is 16.67 mg/mL. Use the calculator on this page for other volumes. This is laboratory math, not a protocol.

What are the reference amounts for GHK-Cu?+

In the research literature GHK-Cu is commonly referenced around 1–2 mg (research literature). At a 50 mg vial in 3 mL that's about 6 units on a U-100 syringe for a 1 mg draw. These are reference values from published research — not a dose, recommendation, or instruction.

How is GHK-Cu verified for purity?+

Every Renova Wellness lot ships with its own per-batch Certificate of Analysis — identity by mass spectrometry and purity by HPLC, tied to the lot number on the vial. You can confirm any lot yourself on the verification page before it leaves the bench.

How should GHK-Cu be stored?+

Lyophilized vials are kept frozen, protected from light and moisture. Once reconstituted with bacteriostatic water, the solution is refrigerated at 2–8°C, protected from light, and avoided from freeze–thaw cycles. General laboratory-handling reference only.

Research references

Primary literature for GHK-Cu. Provided for scientific context only — not medical or dosing guidance.

  1. Maquart FX, et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu²⁺. FEBS Lett. 1988. PMID 3169264
  2. Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018. PMID 29986520

Research Use Only

Sold strictly for in-vitro laboratory and scientific research. Not for human or animal consumption. Not a drug, supplement, or medical device. These statements have not been evaluated by the FDA.