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Research Reference

Semax — Reconstitution & Research Guide

Semax acts on acth(4-10) analog · bdnf modulation and is studied for cognition & neuroprotection research (clinical use (russia) / research). Below: what the research covers, how to reconstitute and verify a vial, and reference values from the literature — framed strictly for laboratory research.

Research use only. This page is a research and laboratory-reference resource — mechanism, reconstitution math, and reference values from published research. It provides no human, veterinary, therapeutic, diagnostic, or administration guidance. Compounds sold by Renova Wellness™ are not approved for human or animal consumption.

Quickstart

Category

cognitive

Vial sizes

10 mg

Reconstitution

10 mg in 2 mL → 5 mg/mL

Reference amount

250–600 mcg (research literature) · ~6 units/draw

Per-batch COA

HPLC purity + mass-spec identity

Storage

Frozen (lyophilized) · 2–8°C reconstituted

What the research covers

Semax acts on ACTH(4-10) analog · BDNF modulation and is studied for cognition & neuroprotection research. Research status: clinical use (russia) / research. The evidence base is largely preclinical and mechanistic; this section summarizes what published work has examined, not outcomes for any product. See the full cited overview in the Semax research guide.

Reconstitution & calculator

Reconstitution is arithmetic: concentration = mg ÷ mL. A tidy option is 1 mL for a round 10 mg/mL (1 mg = 10 units). The tool below is pre-loaded for Semax; type a vial and reference amount and it returns the clean-tick water options, U-100 units, and draws per vial.

Nova — Renova’s research assistant

Guided reconstitution · Powered by Claude

Research use only · not medical advice

  1. 1Draw 2 mL of bacteriostatic water (the volume set in the calculator above) and add it slowly down the inside wall of the vial.
  2. 2Swirl gently until fully dissolved — do not shake. The reconstituted solution should be clear.
  3. 3Label the vial with the date.
  4. 4Refrigerate at 2–8°C, protected from light, and use within the handling window below.

Supply reference

At a 300 mcg reference amount, a 10 mg vial yields about 33 draws — roughly 11 weeks at 3 draws/week. Adjust the amount and cadence in the calculator to plan your own research schedule.

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Storage & handling

  • Lyophilized: keep frozen, protected from light and moisture.
  • Reconstituted: refrigerate at 2–8°C, protected from light.
  • Avoid freeze–thaw of the reconstituted solution.
  • • Allow a frozen vial to reach room temperature before opening. Read the storage guide.

Verify before you trust it

Every Semax lot is third-party tested and ships with its own per-batch Certificate of Analysis — HPLC purity and mass-spectrometry identity, tied to the lot number on your vial. Don’t take our word for it: confirm the exact lot yourself.

Semax FAQ

How do I reconstitute Semax?+

Semax ships lyophilized and is reconstituted with bacteriostatic water. Divide the mg in the vial by the mL of water for the concentration: a 10 mg vial in 2 mL is 5 mg/mL. Use the calculator on this page for other volumes. This is laboratory math, not a protocol.

What are the reference amounts for Semax?+

In the research literature Semax is commonly referenced around 250–600 mcg (research literature). At a 10 mg vial in 2 mL that's about 6 units on a U-100 syringe for a 300 mcg draw. These are reference values from published research — not a dose, recommendation, or instruction.

How is Semax verified for purity?+

Every Renova Wellness lot ships with its own per-batch Certificate of Analysis — identity by mass spectrometry and purity by HPLC, tied to the lot number on the vial. You can confirm any lot yourself on the verification page before it leaves the bench.

How should Semax be stored?+

Lyophilized vials are kept frozen, protected from light and moisture. Once reconstituted with bacteriostatic water, the solution is refrigerated at 2–8°C, protected from light, and avoided from freeze–thaw cycles. General laboratory-handling reference only.

Research references

Primary literature for Semax. Provided for scientific context only — not medical or dosing guidance.

  1. Agapova TY, et al. Neurotrophin gene expression in rat brain under the action of Semax, an analogue of ACTH 4-10. Neurosci Lett. 2007. PMID 17353092
  2. Shadrina MI, et al. Rapid induction of neurotrophin mRNAs in rat glial cell cultures by Semax. Neurosci Lett. 2001. PMID 11457573

Research Use Only

Sold strictly for in-vitro laboratory and scientific research. Not for human or animal consumption. Not a drug, supplement, or medical device. These statements have not been evaluated by the FDA.